Immune System

Support Immune Health: Preventing Colds and Flus With Science-Backed Strategies

By Avni Dalal, ND

As the colder months roll in, many of us start to dread cold and flu season for ourselves and our family members (especially the little ones). While these illnesses are common and may seem an inevitable part of seasonal changes, they can disrupt daily life and put strain on the body as it recovers. The good news? There are actually many proactive steps you can take to support your immune system health and reduce the risk of catching these seasonal bugs. In this blog, we explore practical lifestyle tips and dive into the science behind nutrients and herbal supplements that can help your body stay resilient all year long.

Understanding Cold and Flu Prevention

The key to preventing colds and flus lies in supporting your body’s first line of defense: the immune system. The immune system is a complex network of cells, tissues, and organs that work meticulously to fight off pathogens. Strengthening it requires a multifaceted approach that includes proper nutrition, lifestyle modifications, and considering targeted supplementation.

Lifestyle Tips to Prevent Colds and Flus

Before getting into supplementation, we should first highlight some important tips that can significantly help with cold and flu prevention.

Hand Hygiene

Hygiene is one of the most effective ways to reduce the spread of respiratory viruses. Washing your hands frequently with soap and water for at least 20 seconds, especially after touching high-contact surfaces, is essential.1 If soap and water are not available, using an alcohol-based hand sanitizer with at least 60% alcohol is recommended.1,2 Equally important is avoiding touching your face, particularly your eyes, nose, and mouth, which are common entry points for pathogens.

Adequate Sleep & Regular Exercise

Getting enough sleep is another cornerstone of immune and overall health. Sleep helps the body repair and restore itself, and insufficient rest can compromise the immune system’s ability to ward off infections.2 Aim for 7-9 hours of quality sleep each night and establish a consistent sleep routine to support healthy sleep-wake cycles.

Regular exercise has also been shown to enhance the immune system and lower the risk of respiratory illnesses.3 Moderate-intensity activities like brisk walking or yoga are particularly beneficial.3,4

Stress Management

Managing those stress levels is also a critical aspect of supporting immune function. Exposure to chronic stress can weaken the immune system and increase susceptibility to illness. While some things may feel completely out of our control, incorporating stress-reducing practices like mindfulness meditation, deep breathing exercises, or spending time in nature can help mitigate its effects.

Now that we have covered some practical foundational aspects of supporting immune health, we next delve into the various nutrient and herbal supplements for cold and flu avoidance.

Nutrients for Cold and Flu Prevention

Vitamin C

Vitamin C, often regarded as a fundamental nutrient for immune health, plays an important role in supporting the body’s defenses. This powerful antioxidant protects cells from oxidative stress, which is elevated during infections. It also supports the functions of various immune cells, including neutrophils, lymphocytes, and phagocyres–all of which are crucial for maintaining an effective immune response.5,6 Although vitamin C if found naturally in citrus fruits and berries, regular vitamin C supplementation of 1 to 2 grams per day has been shown to reduce the duration of common cold episodes by 8% in adults and 14% in children, and it decreases the severity of symptoms as well.5*

Vitamin D

Equally important is vitamin D, known as the “sunshine vitamin.” This nutrient helps regulate immune responses and supports the production of antimicrobial peptides, such as cathelicidins and defensins, that combat respiratory infections by lowering viral replication rates and modulating the immune response to reduce inflammation.7* Although sunlight exposure is a natural source of vitamin D, dietary sources like fatty fish and fortified products can also help. For those living in less sunny climates, a supplement providing 1,000-2,000IU is often recommended.*

Zinc

Zinc, an essential mineral, is another powerful ally in immune health. Its strong antioxidant properties contribute to the proper function of immune cells by increasing the production of interferon-gamma and reducing inflammation.8* Additionally, research indicates that taking zinc within the first 24 hours of cold symptoms may shorten their duration by about 33% or about 2 days shorter.9,5 While zinc can be obtained from foods like shellfish, nuts, and whole grains, zinc supplementation at doses of 15-30 mg daily has been shown to be most effective for cold and flu prevention.5,9*

Herbal Supplements for Cold and Flu Prevention

Herbal supplements have been used for centuries across various cultures to support immune system health, and with modern science, we now have backing for the use of these traditional remedies.

  • Elderberry (Sambucus nigra): This berry is rich in flavonoids that possess antiviral properties. Studies have shown that elderberry extract can inhibit viral replication and potentially reduce the severity and duration of colds and flus by enhancing the immune response, making it a popular and tasty choice for seasonal immune support.10*
  • Echinacea: This is another well-studied herb known for its ability to stimulate macrophages and other immune cells, helping the body combat infections more effectively during the early stages of a cold.11*
  • Garlic: This dietary staple is also beneficial for cold and flu prevention due to its ability to improve the function of immune cells, such as natural killer cells, to reduce the severity and duration of symptoms.12 Its ability to combat infections is thanks to its main bioactive compound, allicin, which inhibits viral entry and replication.13
  • Licorice root extract: Another traditionally used herb, it contains glycyrrhizin and glycyrrhetinic acid, which have the ability to provide antiviral properties and support a healthy inflammatory response.14* Glycyrrhizin has been shown to inhibit the replication of various viruses and enhance the antiviral response of our mucosal cells.14

When to Seek Medical Attention for Colds and Flus

While most colds and flus resolve on their own with supportive care, it is important to recognize when professional medical attention is warranted. Symptoms such as high fever (103.1 °F and above) persisting for more than three days, severe difficulty breathing, dehydration, or symptoms that worsen or last longer than 10 days may indicate a more serious condition and require a thorough healthcare evaluation.

Summary

Preventing colds and flus is not only possible but manageable with a combination of healthy habits and targeted nutrient and herbal supplementation. Incorporating immune-supportive nutrients like vitamin C, D, and zinc, along with powerful herbs such as elderberry and echinacea, can proactively strengthen your body’s defenses.* Coupled with lifestyle habits like proper hand hygiene and adequate sleep, these strategies provide a comprehensive approach to staying resilient during cold and flu season.


References:

1. Jefferson T et al. BMJ. 2009;339:b3675.
2. Srivastav A et al. PLoS One. 2018;13(3):e0195085.
3. Alkhatib A. Nutrients. 2020;12(9):2633.
4. Tu R et al. Front Psychol. 2022;13:864515.
5. Rondanelli M et al. Evid Based Complement Alternat Med. 2018;2018:5813095.
6. Hemilä H et al. BMC Public Health. 2023;23(1):2468.
7. Grant WB et al. Nutrients. 2020;12(4):988.
8. Prasad AS et al. J Infect Dis. 2008;197(6):795-802.
9. Science M et al. CMAJ. 2012;184(10):E551-E561.
10. Kim H et al. Comb Chem High Throughput Screen. 2022;25(7):1129-1130.
11. Shah SA et al. Lancet Infect Dis. 2007;7(7):473-480.
12. Nantz MP et al. Clin Nutr. 2012;31(3):337-344.
13. Rouf R et al. Trends Food Sci Technol. 2020;104:219-234.
14. Feng Yeh C et al. J Ethnopharmacol. 2013;148(2):466-473.

About the author

Avni Dalal, ND

Dr. Avni Dalal is a naturopathic physician, writer, and marketing consultant. After completing her clinical training at Sonoran University of Health Sciences in Arizona, she founded her own telehealth practice, Palm and Gold Wellness. She is passionate about empowering individuals through their health journey with a focus on inclusive, comprehensive healthcare for concerns such as PCOS, endometriosis, and PMS/PMDD. Beyond clinical practice, Dr. Dalal has been a medical content writer and marketing consultant for various consumer health and specialty laboratory companies including Nutritional Fundamentals for Health, Allergy Research Group, Mosaic Diagnostics, and Blueroot Health.

Dr. Avni Dalal is a naturopathic physician, writer, and marketing consultant. After completing her clinical training at Sonoran University of Health Sciences in Arizona, she founded her own telehealth practice, Palm and Gold Wellness. She is passionate about empowering individuals through their health journey with a focus on inclusive, comprehensive healthcare for concerns such as PCOS, endometriosis, and PMS/PMDD. Beyond clinical practice, Dr. Dalal has been a medical content writer and marketing consultant for various consumer health and specialty laboratory companies including Nutritional Fundamentals for Health, Allergy Research Group, Mosaic Diagnostics, and Blueroot Health.

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