Magnesium is well known for its myriad health benefits, but knowing which form to choose can be overwhelming and confusing for many. Magnesium supplements come in a variety of forms, some of which are cheaply produced and poorly absorbed. One in particular stands out for its high bioavailability (i.e., easy absorption) and innumerable health benefits: magnesium glycinate.
Magnesium glycinate supplements offer a stress-reducing combination of the essential mineral magnesium combined with glycine, an amino acid known for its ability to soothe and calm the nervous system.1 Its health benefits range from supporting a calming response and promoting restful sleep to supporting muscle function and heart and vascular health. As modern lifestyles increasingly expose us to stress and nutritional deficiencies, understanding the crucial role of a well-absorbed form of magnesium can be a game-changer for overall well-being.
The Importance of Magnesium
Before diving into the specific benefits of magnesium glycinate, it's essential to understand the critical role magnesium plays in our bodies. Magnesium is a key electrolyte and is essential to the healthy functioning of the body. It is involved in over 300 biochemical pathways necessary for good health and is essential for energy production, muscle and nerve function, and bone health, as well as supporting processes for healthy heart rate and blood pressure.
Despite its importance, many people do not get enough magnesium through diet alone as much of the magnesium content of food is lost during processing.1 Additionally, even those who get a substantial amount of unprocessed fruits and vegetables may still be deficient. Studies have shown that our soils now contain less magnesium than they did 50 years ago.1 Furthermore, magnesium deficiency is a frequent side effect of many common drugs including antibiotics, “water-pills” (diuretics), drugs that suppress the immune system, acid-blocking drugs, and chemotherapies.2 It’s easy to see why magnesium deficiency has become so common in Western culture.
Magnesium Deficiency
Magnesium deficiency is an often overlooked and/or completely missed diagnosis because symptoms of deficiency tend to be general (i.e. are common to many other conditions). These symptoms can include wide range of health conditions including muscle cramps/twitches/tremors, weakness, fatigue, underlying and chronic inflammation, sleep disturbances, respiratory issues, weak bones, chronic headaches/migraines, PMS, and menopausal symptoms.2-4
And while ideally we would all be getting enough magnesium from our diet alone, for most of us this isn’t likely. Luckily high-quality magnesium supplements are readily available.
Magnesium Glycinate: A Highly Absorbable Form of Magnesium
Not all magnesium supplements are created equal. Magnesium glycinate is a complex form and combination of magnesium with the amino acid glycine. Because glycine is one of the smallest amino acids, this magnesium complex is more readily absorbed, offering improved bioavailability compared to other magnesium supplements, such as magnesium oxide, which is poorly absorbed. Magnesium complex supplements like this ensure that the magnesium is well-absorbed and therefore accessible to the rest of the body. Magnesium complex with glycine is also gentle on the stomach, reducing the likelihood of gastrointestinal issues commonly associated with other types of magnesium supplements.
The Benefits of Magnesium Glycinate
Promotes Relaxation and Better Sleep
Glycine is well known for its calming effects on the brain.5 In addition, it has been shown to lower core body temperature during sleep, promoting more restful sleep.1 Likewise, magnesium has been shown to improve sleep quality6 and augment calming neurotransmitters, such as GABA7 and improve restlessness8. Together, they can help you unwind after a long day, reduce anxiety, and encourage a restful night's sleep.
Supports Muscle and Nerve Function
Magnesium plays a crucial role in muscle and nerve function. It helps regulate muscle contractions and ensures that nerves send and receive messages properly. Magnesium glycinate can be particularly beneficial for athletes or those who engage in regular physical activity, as it may help to prevent muscle cramps and support muscle recovery. Additionally, for those who experience chronic pain or muscle stiffness, magnesium glycinate can offer significant relief by promoting muscle relaxation.
Bolsters Bone Health
Magnesium plays a pivotal role in bone health, a benefit often overshadowed by more widely recognized bone nutrients like calcium and vitamin D. This essential mineral is crucial for the proper formation and maintenance of bone structure. Magnesium facilitates the activation of vitamin D in the kidneys, which is necessary for calcium absorption.9 Magnesium also helps to regulate hormones responsible for bone health (such as parathyroid hormone and vitamin D), ensuring that calcium is properly utilized. Individuals with higher magnesium intake tend to have higher bone mineral density, underscoring its importance in preventing bone-related disorders.10
Cardiovascular Health
Magnesium is crucial for a healthy heart. It supports a healthy blood pressure11 and aids in maintaining a healthy heart rhythm.12 Magnesium also assists in maintaining healthy arteries13 and contributes to the production of ATP, the energy molecule that fuels heart muscle contractions. Studies have indicated that adequate magnesium intake is associated with heart health and well-being.14
Mental Health Benefits
The calming effects of magnesium glycinate extend beyond better sleep. Magnesium is involved in supporting neurotransmitter function15 and has been shown to help improve low mood and nervousness.16,17 Magnesium glycinate can promote mental well-being and improve stress resilience, improving overall mood.
Incorporating Magnesium Glycinate Into Your Routine
In the quest for optimal health and wellness, magnesium glycinate emerges as a standout supplement with a host of benefits. From enhancing sleep quality and supporting muscle function to promoting heart health and alleviating anxiety, this versatile compound offers a holistic approach to well-being. By incorporating magnesium glycinate into your daily routine, you can unlock a healthier, more balanced life. As with any supplement, it's important to consult with a healthcare professional before starting to ensure it's appropriate for your individual needs.
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Improving Occasional Constipation With Magnesium
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The Magnesium-Cortisol Connection
Comparing the Different Types of Magnesium Supplements
References
1. Kawai N et al. Neuropsychopharmacology. 2015;40(6):1405-1416.
2. Parazzini F et al. Magnes Res. 2017;30(1):1-7.
3. Cazzola R et al. Heliyon. 2020;6(11):e05390.
4. Touyz RM et al. N Engl J Med. 2024;390(21):1998-2009.
5. Kawai N et al. Neuropsychopharmacology. 2015;40(6):1405-1416.
6. Abbasi B et al. J Res Med Sci. 2012;17(12):1161-1169.
7. Stanojević M et al. Biol Trace Elem Res. Published online May 6, 2024.
8. Gorantla S et al. J Clin Sleep Med. Published online May 13, 2024.
9. Uwitonze AM et al. J Am Osteopath Assoc. 2018;118(3):181-189.
10. Rondanelli M et al. Biometals. 2021;34(4):715-736.
11. Dibaba DT et al. Am J Clin Nutr. 2017;106(3):921-929.
12. Tangvoraphonkchai K et al. Adv Chronic Kidney Dis. 2018;25(3):251-260.
13. Yue J et al. Biochem Biophys Res Commun. 2016;478(1):314-322.
14. Song J et al. Biol Trace Elem Res. Published online June 4, 2024.
15. Maier JAM et al. Int J Mol Sci. 2022;24(1):223.
16. Eby GA et al. Med Hypotheses. 2006;67(2):362-370.
17. Rawji A et al. Cureus. 2024;16(4):e59317.
